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Feelings of fullness increased from baseline in all treatment groups (significantly at most time points), with no significant differences between the retatrutide and placebo or dulaglutide groups at any time point (Figure 1 and Supplementary Figure 2D)

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The oral GLP-1 space is advancing too, with orforglipron versus tirzepatide representing a potential future where daily pills replace weekly injections

Compounded versions of GLP-1 (glucagon-like peptide-1) drugs are within easier reach of some of the nearly three-quarters of Americans who are overweight or obese

Associations of semaglutide with first-time diagnosis of Alzheimers disease in patients with type 2 diabetes: target trial emulation using nationwide real-world data in the US